Examples

采取重大措施

adopt an important measure → 措施

考古方面的重大发现

important archaeological finds → 发现

亟待解决的重大问题

important problems demanding prompt solution → 亟

重大技术改革

key technological transformations → 技术

人类认识史上的重大建树

major attainments in the history of human knowledge → 建树

这本书填补了词典学方面的重大缺门。

This book fills a major gap in lexicography. → 缺门

事关重大，请你三思。

It's a matter of great importance. I would advise you to think carefully. → 三思

双方的分歧涉及一些重大原则性问题。

The differences between the two sides involve major matters of principle. → 涉及

重大损害

substantial damage → 损害

遭受重大损失

suffer (or sustain) heavy losses → 损失

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